Pharmacokinetic Study of Biliary Excretion. II. Comparison of Excretion Behavior in Triphenylmethane Dyes
نویسندگان
چکیده
منابع مشابه
Biliary excretion in foreign compounds. Species difference in biliary excretion.
1. The biliary excretion of injected [(14)C]aniline, [(14)C]benzoic acid, 4-amino-hippuric acid and 4-acetamidohippuric acid in six or eight species of animal (rat, dog, hen, cat, rabbit, guinea pig, rhesus monkey and sheep) was studied. 2. These compounds, with molecular weights in the range 93-236, are poorly excreted in the bile in all the species examined and, in effect, there is little sig...
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During the process of hepatic excretion, a diverse group of exogenous organic compounds and endogenous metabolites is conjugated with polar anionic molecules (1). Although it is clear that the physical and chemical characteristics of these compounds can be drastically altered by conjugation, the relationship between conjugation and excretion has not been fully elucidated (2). Formation of the g...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1971
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.19.273